PROteolysis TArgeting Chimeras (PROTACs)- 2 decades of research

Table of Contents Researchers are investigating PROteolysis TArgeting Chimeras (PROTACs) as a potential treatment for cancer, neurodegenerative diseases, and other challenging conditions. PROTACs are small molecules that utilize the ubiquitin-proteasome system to degrade specific proteins. They function by linking the target protein to an E3 ligase, triggering its degradation while the PROTAC itself is recycled […]