Analytical Chemistry Services

Analytical Chemistry Services for Discovery Chemistry

Zasya Life Sciences offers comprehensive analytical services tailored to support early-phase drug discovery and development.

We offer services for NCEs (New Chemical Entities), APIs, and formulations of drug substances (DS) and drug products (DP), ensuring support for discovery and development needs.

Zasya Analytical Services

Analytical Method Development and Validation

Development of analytical methods for assay, impurities, and dissolution studies.
Validation according for reproducibility, accuracy, and precision.
Method optimization and transfer for seamless integration into downstream processes.

Impurity Profiling and Isolation

Identification, characterization, and isolation of related substances, degradation products, and metabolites. Genotoxic impurity (GTI) studies to ensure compliance with regulatory standards. Structural elucidation of impurities using advanced spectroscopic and chromatographic techniques.

Purification Services

Flash chromatography
Supercritical Fluid Chromatography (SFC):Achiral and chiral purification for high-purity outputs.
Prep purification using reverse phase, normal phase, and chiral chromatography.

Stability Studies

Comprehensive stability studies for drug substances and products under various storage conditions.
Impartial and long-term stability evaluations for regulatory submissions.
Forced degradation studies to determine degradation pathways.

Structural and Physicochemical Characterization

Complete structure elucidation of NCEs, impurities, and degradation products using LC-HRMS, NMR, FT-IR, and UV-Vis spectroscopy.
Physicochemical studies including melting point, solubility, pKa, and Log P determination.