PXRD is used to determine the crystalline structure, polymorphism, and phase transitions of solid compounds. This technique aids in the identification of crystalline phases and their purity, which is important for optimizing drug formulations and ensuring consistency in quality.
DSC is used to measure the heat flow associated with material transitions such as melting, crystallization, and glass transition. This technique helps us understand the thermal properties of materials, which can provide insights into stability, formulation development, and excipient compatibility.
TGA measures changes in a material’s weight as it is heated, which helps to determine thermal stability, moisture content, and volatile components. This technique is especially useful for assessing the stability and purity of drug substances and excipients.